P1.239. Clinical Outcomes of Conversion Surgery for Locally Advanced Esophageal Cancer With Mediastinal M1b Lymph Node Metastasis

Clicks: 17
ID: 326198
2026
Free PDF
Article Quality & Performance Metrics
Overall Quality
Not rated
Combines reader engagement with the AI quality analysis. This article has not been analysed, so there is no overall score — reader engagement is measured and shown alongside.
AI Quality Assessment
Not analyzed
Readership in this journal
Emerging

Ranked #402 of 453 articles by views in diseases of the esophagus : official journal of the international society for diseases of the esophagus

Most read Least read

Bar heights use a square-root scale. Only the 120 most-read articles are drawn; the journal has 453 in total.

Mint this article as an NFT
Not yet minted

Create a permanent, verifiable on-chain record of this article on the Scimatic Network. The NFT is held in your Journament account, and you can withdraw it to your own wallet at any time.

5 SUSD one-off · no wallet required
Sign in to mint
Abstract
Abstract Topic Esophageal Cancer: Surgical Treatment of Esophageal Cancer – long term outcomes Background The role of conversion surgery (CS) for locally advanced esophageal cancer with mediastinal M1b lymph node metastasis has not yet been clearly defined. Methods We evaluated the therapeutic outcomes of 27 patients who underwent conversion surgery (CS) for locally advanced esophageal cancer with mediastinal M1b lymph node metastasis, among 1,030 patients who underwent thoracic esophagectomy at our institution between January 2011 and November 2023. Results The number of patients with mediastinal M1b lymph node metastases (114/113/106pre/106tbR/112Ao-P) were 12/4/12/12/1/4, respectively (duplicate results). Preoperative therapy (CF/DCF/CRT) was administered to 7/15/4 patients, respectively. The response rate of preoperative treatment was 85%. Postoperative adjuvant chemotherapy (none/Nivo) was given in 0/3 of the patients. Short-term postoperative outcomes were suture failure in 4 patients (15%), pneumonia in 7 patients (27%), recurrent nerve palsy in 4 patients (15%), and no in-hospital death. Postoperative recurrence was observed in 15 patients (56%). The 3-year postoperative recurrence-free survival (PFS) rate was 52%, and the 3-year overall survival (OS) rate was 63%. 3-year PFS by distant lymph node (114 or 113 node/106pre or 106tbR node/112Ao-P node) was 60%/23%/75%, respectively. The 3-year OS was 67%/38%/75%, respectively. The short-term postoperative outcomes were acceptable in all cases, with 113/114 lymph node metastases and 112Ao-P metastases having a relatively better prognosis than 106pre/106tbR metastases. Conclusion CS may have significance in locally advanced esophageal cancer with mediastinal M1b lymph node metastasis as part of multimodality treatment in the case of anterior mediastinal lymph node metastasis and 112Ao-P.
Reference Key
openalex_W7204002963 Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Tetsuya Abe, Takahiro Hosoi, Kosuke Inada, Kotaro Ozaki, Eiji Higaki
Are you one of these authors? Claim your profile
Journal diseases of the esophagus : official journal of the international society for diseases of the esophagus
Year 2026
DOI
10.1093/dote/doag077.387
URL
https://academic.oup.com/dote/article-pdf/39/Supplement_1/doag077.387/70760687/doag077.387.pdf
Keywords Keywords not found

Citations

No citations found. To add a citation, contact the admin at info@scimatic.org

Comments

No comments yet. Be the first to comment on this article.