Beyond fibroblast activation: expanding the role of the AREG–EGFR axis in keloid pathogenesis

Clicks: 1
ID: 325835
2026
Article Quality & Performance Metrics
Overall Quality
Not rated
Combines reader engagement with the AI quality analysis. This article has not been analysed, so there is no overall score — reader engagement is measured and shown alongside.
AI Quality Assessment
Not analyzed
Readership in this journal

Ranked #295 of 300 articles by views in the british journal of dermatology

Most read Least read

Bar heights use a square-root scale. Only the 120 most-read articles are drawn; the journal has 300 in total.

Mint this article as an NFT
Not yet minted

Create a permanent, verifiable on-chain record of this article on the Scimatic Network. The NFT is held in your Journament account, and you can withdraw it to your own wallet at any time.

5 SUSD one-off · no wallet required
Abstract
We comment on the recent study by Dong et al., which identified the AREG–EGFR axis as a key driver of fibroblast activation and extracellular matrix deposition in keloids. We expand their findings by discussing the potential roles of immune–stromal interactions, EGFR downstream signalling complexity, extracellular matrix mechanobiology, and ligand-specific targeting within the EGFR network. These perspectives may help refine the mechanistic understanding of AREG signalling and guide the development of more precise therapeutic strategies for keloids.
Reference Key
openalex_W7203873609 Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Zihao Li, Yucang He, Liqun Li, Songyun Zhao
Journal the british journal of dermatology
Year 2026
DOI
10.1093/bjd/ljag350
URL
Keywords Keywords not found

Citations

No citations found. To add a citation, contact the admin at info@scimatic.org

No comments yet. Be the first to comment on this article.