P1.099. Esophageal Cancer After Distal Gastrectomy

Clicks: 6
ID: 325730
2026
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Ranked #318 of 453 articles by views in diseases of the esophagus : official journal of the international society for diseases of the esophagus

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Abstract
Abstract Topic Esophageal Cancer: Esophageal Carcinogenesis Background The effect of gastrectomy on the subsequent development of esophageal cancer was investigated. Duodenogastroesophageal reflux is thought to be common in patients after distal gastrectomy, but whether this contributes to the development of esophageal cancer in such patients is controversial. Methods We retrospectively evaluated 153 patients who underwent subtotal esophagectomy for thoracic esophageal cancer for the past three years. They were divided into two groups, according to whether or not they had previously undergone a gastrectomy: group 1, comprising 14 patients who had undergone gastrectomy and group 2, comprising 139 patients who had not. Clinical profiles of the patients were obtained from the medical records and the whole resected esophagus was histopathologically examined. Results The interval between gastrectomy and esophagectomy in group 1 was significantly shorter in the patients who had undergone gastrectomy for gastric cancer (10.5 ± 4.2 years) than in those who had undergone gastrectomy for a peptic ulcer (28.9 ± 3.0 years). The interval was also somehow shorter in the patients for whom anastomosis had been performed by Billroth I (21.3 ± 5.6 years) compared with Billroth II (29.7 ± 3.2 years), although the difference did not reach its statistical significance (P = 0.11). Moreover, the proportion of lower third tumors in patients after gastrectomy was significantly higher compared with that of the patients with intact stomach. Conclusion These findings suggest that a history of gastrectomy is associated with more lower-third squamous cell esophageal carcinoma.
Reference Key
openalex_W7203905418 Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Naoki Hashimoto
Journal diseases of the esophagus : official journal of the international society for diseases of the esophagus
Year 2026
DOI
10.1093/dote/doag077.247
URL
https://doi.org/10.1093/dote/doag077.247
Keywords Keywords not found

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