P1.045. Management of a Large Esophagojejunostomy Defect After Laparoscopic Total Gastrectomy Using Endoscopic Vacuum Therapy and Adjunctive Stenting

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ID: 325679
2026
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Ranked #103 of 453 articles by views in diseases of the esophagus : official journal of the international society for diseases of the esophagus

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Abstract
Abstract Topic Benign Disease: Other Background Esophagojejunostomy (EJ) leakage after total gastrectomy remains a life-threatening complication. While endoscopic vacuum therapy (EVT) has emerged as an effective treatment option, management of large anastomotic disruption and subsequent stenosis remains challenging. We report a case successfully managed with repeated EVT and subsequent stent placement. Methods An 80-year-old woman with antral gastric cancer underwent planned totally laparoscopic distal gastrectomy. After ligation of the left gastric artery, poor remnant gastric perfusion was noted, and the procedure was converted to totally laparoscopic total gastrectomy with Roux-en-Y esophagojejunostomy. Results On postoperative day (POD) 7, the patient developed fever. Computed tomography demonstrated loculated fluid–air collection and free air, raising suspicion of anastomotic leakage. Emergency reoperation revealed disruption of the EJ anastomosis. Continuous primary repair and sump drainage were performed. On POD 10 after reoperation, enteric content was observed through the sump drain. Endoscopy confirmed a large peri-anastomotic defect. Endoscopic vacuum therapy (EVT) was initiated and performed six times over three weeks until marked reduction of the defect was achieved. Follow-up endoscopy demonstrated mucosal healing but significant anastomotic stenosis associated with dysphagia, requiring endoscopic stent insertion. Endoscopic stent placement was successfully performed to relieve obstruction and maintain luminal patency. Following stenting, oral intake was gradually resumed without recurrence of leakage Conclusion Prolonged EVT is an effective minimally invasive strategy for managing extensive EJ anastomotic disruption after total gastrectomy. Even in cases requiring multiple sessions, satisfactory defect closure can be achieved without additional major surgery. Anastomotic stenosis following healing may occur but can be effectively managed with endoscopic stent placement. Combined endoscopic approaches may offer a viable organ-preserving alternative in complex postoperative leakage.
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Authors J. Noh, Ji Yeon Park, Ki Bum Park, Hyun Wook Shin, Oh Kyoung Kwon
Journal diseases of the esophagus : official journal of the international society for diseases of the esophagus
Year 2026
DOI
10.1093/dote/doag077.193
URL
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