LF1 mediates brassinosteroid signaling to regulate leaf angle development in rice

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ID: 325162
2026
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Abstract
Abstract Leaf angle is a key determinant of plant architecture and grain yield in rice, yet the complex genetic regulatory network remains unclear. Here, we reveal that the HD-ZIP III transcription factor LF1 mediates BR signaling to modulate leaf angle. A miRNA165/166-resistant, gain-of-function lf1 mutant displays an enlarged leaf angle driven by elongated adaxial parenchymal cells and diminished abaxial sclerenchyma. At the transcriptional level, the BR-activated transcription factor OsBZR1 directly induces LF1, which in turn upregulates OsOFP8, forming an OsBZR1-LF1-OsOFP8 hierarchical transcriptional cascade that mediates BR signaling to regulate leaf angle development. At the post-translational level, LF1 protein stability is fine-tuned by reciprocal post-translational modifications, wherein OsMAPK6-mediated phosphorylation at Thr148 promotes LF1 accumulation and transcriptional activity, directly counteracting its ubiquitination and degradation by the APC/CTAD1 complex. Genetic analyses demonstrate that LF1, OsMAPK6, and TAD1 function in a common pathway to regulate leaf angle development. Overall, our study establishes LF1 as a central hub coupling transcriptional and post-translational mechanisms to modulate BR-mediated leaf angle, providing targets for plant architecture improvement.
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openalex_W7203632138 Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Jing You, Bingyu Ning, Yi Zhang, Jichao Zhang, Wenwen Xiao, Yan Chen, Jianyan Mu, Zheng Zhongyi, Mo Yunyan, Wang Yuxin, Xianchun Sang, Yinghua Ling, Guanghua He, Ting Zhang
Journal The Plant cell
Year 2026
DOI
10.1093/plcell/koag247
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