Early-life dietary patterns and the risk of juvenile-onset ankylosing spondylitis: a nationwide cohort study in South Korea

Clicks: 1
ID: 325119
2026
Free PDF
Article Quality & Performance Metrics
Overall Quality
Not rated
Combines reader engagement with the AI quality analysis. This article has not been analysed, so there is no overall score — reader engagement is measured and shown alongside.
AI Quality Assessment
Not analyzed
Readership in this journal

Ranked #178 of 197 articles by views in Lara D. Veeken

Most read Least read

Bar heights use a square-root scale. Only the 120 most-read articles are drawn; the journal has 197 in total.

Mint this article as an NFT
Not yet minted

Create a permanent, verifiable on-chain record of this article on the Scimatic Network. The NFT is held in your Journament account, and you can withdraw it to your own wallet at any time.

5 SUSD one-off · no wallet required
Sign in to mint
Abstract
Abstract Objectives Emerging evidence suggests that early-life exposures may influence the development of inflammatory joint diseases. This study investigated the association between early-life exposures and the incidence of juvenile-onset ankylosing spondylitis (JAS) in a nationwide South Korean cohort. Methods This study included 1,242,257 infants from the South Korean National Health Insurance Service. The association between early-life exposures—such as food diversity, frequency of solid food intake, antibiotic use, and breastfeeding status—and the development of JAS, was examined. Food diversity and frequency of solid food intake were assessed at the 9-12 month screening visit, breastfeeding status was assessed at the 4-6 month and 9-12 month screening visit, and antibiotic use was based on prescription records within the first year after birth. Subgroup analyses were conducted according to food diversity levels. Adjusted hazard ratios (aHRs) and 95% confidence intervals (CIs) were calculated using Cox proportional hazards models. Results Food diversity and breastfeeding alone were not associated with JAS. However, breastfeeding in infants with high food diversity was linked to a reduced risk of JAS. (aHR 0.53, 95% CI 0.31-0.90, p = 0.0195) Conclusion Pediatrics with high food diversity who were breastfed showed reduced vulnerability to JAS. These findings suggest that maintaining a consistent and appropriate dietary pattern may play an important role in the prevention of JAS.
Reference Key
openalex_W7203609331 Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Seyun Lee, Junhyun Kwon, Woo-Jeong Shon, Joo Sung Kim, Byeong Gwan Kim, Jong Pil Im, Hyun Lee, Min Jung Kim, Hyunsun Park, Seong‐Joon Koh
Journal Lara D. Veeken
Year 2026
DOI
10.1093/rheumatology/keag433
URL
https://doi.org/10.1093/rheumatology/keag433
Keywords Keywords not found

Citations

No citations found. To add a citation, contact the admin at info@scimatic.org

Comments

No comments yet. Be the first to comment on this article.