CRP at diagnosis in psoriatic arthritis: what it means and associations with long-term outcomes
Clicks: 1
ID: 324237
2026
Article Quality & Performance Metrics
Overall Quality
Not rated
Combines reader engagement with the AI quality analysis. This
article has not been analysed, so there is no overall score —
reader engagement is measured and shown alongside.
Reader Engagement
0.0
/100
1 views
0 readers
AI Quality Assessment
Not analyzed
Readership in this journal
Ranked #46 of 197 articles by views in Lara D. Veeken
Most read
Least read
Bar heights use a square-root scale. Only the 120 most-read articles are drawn; the journal has 197 in total.
Mint this article as an NFT
Not yet mintedCreate a permanent, verifiable on-chain record of this article on the Scimatic Network. The NFT is held in your Journament account, and you can withdraw it to your own wallet at any time.
5
SUSD
one-off · no wallet required
Abstract
OBJECTIVE: The role of C-reactive protein (CRP) in Psoriatic Arthritis (PsA) as a diagnostic and prognostic marker is debated. We compared clinical and epidemiological features, as well as long-term outcomes, between patients with "elevated" (>0.5 mg/dL) and patients with "normal" (≤0.5 mg/dL) CRP at diagnosis. METHODS: In this real-world study, we analyzed data from 609 PsA patients categorized by their CRP at diagnosis. Demographics, clinical characteristics, comorbidities, and long-term outcomes were compared. The statistically significant variables in the univariate analyses were used to build two multivariable logistic regression models: i. assessing associations between CRP and features at PsA diagnosis, ii. examining its link with long-term outcomes (including "difficult to manage" and "persistent disease") and characteristics throughout the disease course. RESULTS: Of 609 patients, 132 (21.7%) displayed normal and 477 (78.3%) elevated CRP values at diagnosis. By univariate analysis, elevated CRP was associated with longer disease follow-up, BMI > 25 Kg/m2, enthesitis (at diagnosis and disease course), hypertension, hyperuricemia, new bone formation and "persistent disease". By multivariable analyses, elevated CRP at diagnosis was independently linked with BMI >25 Kg/m2 (OR 1.69, 95% CI 1.05-2.72), enthesitis (OR 2.04, 95% CI 1.24-3.38), hypertension (OR 2.07, 95% CI 1.04-4.11), new bone formation (OR 2.57, 95% CI 1.33-4.94), and "persistent disease" (OR 4.36, 95% CI 2.22-8.59). CONCLUSION: Overall PsA characteristics are comparable, irrespective of the CRP-levels at diagnosis, apart from new bone formation, enthesitis, "persistent disease" and increased cardiometabolic burden which were independently associated with elevated CRP-levels at PsA diagnosis.
| Reference Key |
openalex_W7201838710
Use this key to autocite in the manuscript while using
SciMatic Manuscript Manager or Thesis Manager
|
|---|---|
| Authors | Angeliki E. Dimopoulou, C Papagoras, Niki Kyriazi, Sousana Gazi, Evangelia Mole, Michael Krikelis, Paraskevi V Voulgari, Evripidis Kaltsonoudis, Nikolaos Koletsos, P. Katsimpri, Dimitrios Boumpas, Dimitrios Katsifis-Nezis, Nikolaos Kougkas, Theodoros Dimitroulas, Petros P Sfikakis, Maria G. Tektonidou, Konstantinos D Vassilakis, D.P. Bogdanos, Theodora Simopoulou, Christos Koutsianas, Eugenia Mavrea, Gkikas Katsifis, Konstantinos Kottas, Maria Konsta, Matthoula Tziafalia, Evangelia Kataxaki, Eleni Kalavri, Kalliopi Klavdianou, Αναστάσιος Καραμανάκος, Ioannis Xynogalas, Dimitrios Daoussis, George Iliopoulos, Ilias Bournazos, Konstantinos Georganas, Dimos Patrikos, Dimitrios Vassilopoulos, George E Fragoulis |
| Journal | Lara D. Veeken |
| Year | 2026 |
| DOI |
10.1093/rheumatology/keag398
|
| URL | |
| Keywords | Keywords not found |
Citations
No citations found. To add a citation, contact the admin at info@scimatic.org
Comments
No comments yet. Be the first to comment on this article.