TPW 6.05 Clinical Outcomes and Survival Following Endoscopic Ultrasound-Guided Gastroenterostomy for Malignant Gastric Outlet Obstruction

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ID: 323963
2026
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Abstract
Abstract Aims Endoscopic ultrasound-guided gastroenterostomy (EUS-GE) is an alternative to duodenal stenting and surgical gastrojejunostomy for malignant gastric outlet obstruction (GOO), aiming to provide durable luminal patency with fewer procedure-related morbidities. This study evaluated clinical outcomes, complications, and survival following EUS-GE in malignant GOO. Methods Data were collected prospectively for consecutive patients undergoing EUS-GE for malignant GOO and analysed retrospectively. Indications included advanced malignant disease causing symptomatic GOO, primarily in a palliative setting, including patients unsuitable for surgery. Demographic data, procedural details, technical success, complications, and length of hospital stay were recorded. Survival status was determined from clinical records, and survival time was analysed using Kaplan–Meier methods. Results Twenty patients were included (median age 75 years; IQR 62–80). All underwent EUS-GE using a 20 mm × 10 mm lumen-apposing metal stent. Nineteen procedures were performed under conscious sedation, and one with propofol. Technical success was achieved in 19/20 patients (95%), with one failure due to early stent maldeployment. Median post-procedure length of stay was 3.5 days (IQR 2–7.5). Thirty-day mortality was 9/20 (45%). Kaplan–Meier estimated survival was 90% at 7 days, 55% at 30 days, and 35% at 90 days. During a total follow-up period of 1441 days, 15 patients died. Conclusions EUS-guided gastroenterostomy demonstrated high technical success, short hospital stay, and low complication rates in malignant GOO. While early mortality reflects advanced disease stage, outcomes align with comparative evidence supporting EUS-GE as a safe and effective alternative to duodenal stenting and surgical gastrojejunostomy in appropriately selected patients.
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Authors Swarna Kempe Gowda, Nasir Javed, Roderick Prawiradiradja, C V N Cheruvu, Sirisha Hebbar
Journal the british journal of surgery
Year 2026
DOI
10.1093/bjs/znag087.358
URL
https://doi.org/10.1093/bjs/znag087.358
Keywords Keywords not found

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