TPTh 8.07 Postoperative Ileus (POI) in Colorecta Colorectal (CRC) Resections: A Cohort Study

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ID: 323908
2026
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Abstract
Abstract Aims POI is prevalent-complication that occurs in <30 % of CRC-resections, associated with increased-hospitalization, morbidity & healthcare-costs. Aim -of-study: to evaluate the-effects of POI in CRC-resections. Methods Cohort-study carried-out from Jan 2007 to Jan 2026 at single centre. Descriptive-demography & post-operative outcomes were assessed for POI-patients in CRC-resections, non-ileus CRC-resections were recruited as controls. Results POI(n=315) Non-ileus(n=1679) Mann-Whitney-U(p-value) Age(yrs) 71.8±0.7 69.9±0.3 NS Sex(M:F) 216:99 871:808 <0.0001 ASA 2±0.5 2±0.5 NS BMI(kg/m2) 27.1±0.3 26.5±0.1 NS Emergency(n) 66 363 NS Laparoscopic(n) 181 1028 NS Leaks(n) 21 58 NS HAP(n) 70 132 <0.0001 SRI’s(n) 42 123 NS Collection(n) 34 87 NS Sepsis(n) 47 73 < 0.01 Op-time(mins) 192.2±4.8 173.7±2.2 <0.0005 LOS(days) 14±6 7 ±3.5 <0.0001 POI-onset(days) 4±1.5 NG tube(days) 3±1.5 TPN(n) 37 Day4-WCC(x109/L) 9.4±0.3 9.6±0.2 NS Day4-CRP(mg/L) 180.9±6.4 146.8±3.6 <0.0001 POI-diagnosis(n) Clinical 65 AXR 74 Gastrograffin 66 CT scan 138 Conclusion POI occurred in 15.7 % of all CRC-resections at-our-institution. Diagnosis of POI made on day-4 (predominantly-radiologically), requiring 3-days of NG-decompression, prolonged-ileus (>7 days) required parenteral-nutrition. POI is usually self-limiting, arises from complex-effects of inflammatory & neurogenic-stresses and compounded by pharmacologic-triggers. POI should be managed in multidisciplinary-multimodal coordinated-manner: team-collaboration (surgeons, anaesthetists, pharmacists, nurses & dietitians). pharmacological-agents (opioid minimization & prokinetic use), behavioural & lifestyle (early feeding & ambulation, coffee), surgical techniques (minimal invasive surgery), & supportive care (fluid & electrolyte replacements, NG-tube decompression, early enteral nutrition).
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Authors M A Gok, K Riaz, S Khan, H E Huguet, R U Aris, U A Khan
Journal the british journal of surgery
Year 2026
DOI
10.1093/bjs/znag087.509
URL
https://doi.org/10.1093/bjs/znag087.509
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