Patient-Specific Multimodal Learning with Multi-View Contrastive Alignment for Chest X-ray Report Generation

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ID: 322872
2026
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Abstract
MOTIVATION: Radiology reports play a pivotal role in guiding treatment planning and enabling effective doctor-patient communication. However, their manual composition imposes a substantial workload on radiologists. Although automatic radiology report generation has emerged as a promising alternative, existing approaches predominantly rely on single-view chest X-rays and fail to adequately leverage patient-specific context, thereby limiting diagnostic accuracy. RESULTS: To address this challenge, we propose EVOKE, a novel chest X-ray report generation framework that incorporates multi-view contrastive learning and patient-specific knowledge. Specifically, we introduce a multi-view contrastive learning method that captures semantic correspondences both among multi-view radiographs within a study and between these radiographs and their associated report, thereby improving visual representation learning. We further present a knowledge-guided report generation module that integrates available patient-specific knowledge (i.e., indication, which includes symptom descriptions) to facilitate the generation of accurate and coherent radiology reports. To support research in multi-view report generation, we construct Multiview CXR and Two-view CXR datasets using publicly available sources. Our proposed EVOKE surpasses recent state-of-the-art methods across multiple datasets, achieving a 2.9% F1 RadGraph improvement on MIMIC-CXR, a 5.0% BLEU-1 improvement on MIMIC-ABN, a 1.5% BLEU-4 improvement on Multi-view CXR, and an 8.2% F1,mic-14 CheXbert improvement on Two-view CXR. AVAILABILITY: Code is publicly available at https://github.com/mk-runner/EVOKE, with an archived release available on Zenodo (doi:10.5281/zenodo.21000219).
Reference Key
openalex_W7171525642 Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Qiguang Miao, Kang Liu, Zhuoqi Ma, Yunan Li, Xiaolu Kang, Ruixuan Liu, Tianyi Liu, Kun Xie
Journal BMC Bioinformatics
Year 2026
DOI
10.1093/bioinformatics/btag566
URL
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