Generalized Bullae in a Child

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ID: 322129
2026
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Abstract
A 2.5-year-old boy presented with generalized pruritic bullae misdiagnosed as allergic dermatitis for two years. Histopathology with Giemsa stain confirmed mast cell infiltration, establishing a diagnosis of bullous mastocytosis. This case highlights the importance of early skin biopsy with special stains in children with chronic bullous eruptions and negative autoimmune serology.
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Authors Yue Wang, Lin Cheng, Qun Wei, Chun-fang Guo, Zhen Wang
Journal the british journal of dermatology
Year 2026
DOI
10.1093/bjd/ljag282
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