Increased Efficacy of Daytime Low-dose Oral Minoxidil Dosing for Androgenetic Alopecia: A Retrospective Study

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ID: 321146
2026
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Abstract
The timing of low-dose oral minoxidil (LDOM) administration may influence treatment outcomes in androgenetic alopecia (AGA). In this retrospective observational study of 329 patients, daytime LDOM dosing was associated with significantly greater improvements in hair density compared to nighttime dosing, both on univariable and multivariable analysis. These findings suggest that circadian variation in hair follicle biology may have clinical implications for optimizing LDOM therapy in AGA.
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openalex_W7168370358 Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Derek Maas, Archie Spindler, Isabella Zappi, Margaret Cote, Jolie Kantor, Esha Patel, Sarah Go, Ian M Ahearn, Ian W Tattersall, Lynn Petukhova, Jerry Shapiro, Kristen I Lo Sicco
Journal the british journal of dermatology
Year 2026
DOI
10.1093/bjd/ljag280
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