Integrated multi-omics and functional dissection of RING-type E3 ubiquitin ligases in flowering-time control in Setaria

Clicks: 3
ID: 321113
2026
Free PDF
Article Quality & Performance Metrics
Overall Quality
Not rated
Combines reader engagement with the AI quality analysis. This article has not been analysed, so there is no overall score — reader engagement is measured and shown alongside.
AI Quality Assessment
Not analyzed
Readership in this journal

Ranked #100 of 281 articles by views in Journal of experimental botany

Most read Least read

Bar heights use a square-root scale. Only the 120 most-read articles are drawn; the journal has 281 in total.

Mint this article as an NFT
Not yet minted

Create a permanent, verifiable on-chain record of this article on the Scimatic Network. The NFT is held in your Journament account, and you can withdraw it to your own wallet at any time.

5 SUSD one-off · no wallet required
Sign in to mint
Abstract
Flowering time is a key adaptive and agronomic trait determining regional suitability and yield stability in plants. Although ubiquitin-mediated protein degradation regulates diverse developmental and stress responses, the role of RING-type E3 ubiquitin ligases in flowering-time control in plants remains relatively underexplored. Here, we conducted an integrated multi-omics analysis to investigate the contribution of RING-type E3 ligases to flowering-time regulation in Setaria italica. We identified 496 RING-type E3 ligases in the Setaria genome and revealed extensive family expansion driven by whole-genome duplication and lineage-specific duplication events. By integrating transcriptome profiling under contrasting photoperiods with flowering-time QTL mapping, we identified three candidate RING-type E3 ligases, including SGD1. Population genomics and haplotype analyses across 1,433 Setaria accessions uncovered functional polymorphisms in these genes associated with variation in flowering time and yield-related traits. Functional analyses demonstrated that SGD1 modulates both flowering time and grain yield by regulating the stability of the transcription factor SiSPL2, thereby reshaping downstream transcriptional networks related to photoperiod signaling and metabolism. Joint haplotype analyses further revealed additive effects between SGD1 and SiSPL2, providing a framework for haplotype-guided breeding. Together, our study highlights ubiquitin-mediated post-translational regulation as an important layer in flowering-time control and yield adaptation in cereal crops.
Reference Key
openalex_W7168384926 Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Linlin Zhang, Sha Tang, Yannan Wang, Hailin Fu, Decheng Yin, Zaixu Zhou, Yuanzhu Gao, Yang Zhang, Haoying Wei, Qiaoling He, Hui Zhi, Guanqing Jia, Jinjuan Yu, Xianmin Diao
Journal Journal of experimental botany
Year 2026
DOI
10.1093/jxb/erag347
URL
https://doi.org/10.1093/jxb/erag347
Keywords Keywords not found

Citations

No citations found. To add a citation, contact the admin at info@scimatic.org

Comments

No comments yet. Be the first to comment on this article.