Renal replacement therapy: current modalities, indications, and clinical considerations

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ID: 321060
2026
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Abstract
Abstract Chronic kidney disease (CKD) is a significant global health issue, affecting ~10% of the world’s population. In the USA, nearly 90% of adults with CKD are unaware of their condition, leading to delays in care and, in many cases, progression to end-stage kidney disease (ESKD) requiring renal replacement therapy (RRT). It is important to recognize that not all individuals with CKD will develop kidney failure. RRT options include hemodialysis (HD), peritoneal dialysis (PD), and kidney transplantation. Prior to initiating HD, a vascular access such as an arteriovenous (AV) fistula, AV graft, or central venous catheter, must be placed, typically by a vascular surgeon. In contrast, PD requires a surgically implanted catheter in the abdomen. This paper reviews the available RRT modalities and emphasizes the importance of offering conservative management as an alternative approach. Additionally, we explore emerging innovations such as wearable and portable HD devices, that have the potential to transform ESKD care and significantly improve patients’ quality of life.
Reference Key
openalex_W7168374488 Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Laurena Dongmo Fotsing, Jay H Shubrook
Journal the nigerian postgraduate medical journal
Year 2026
DOI
10.1093/postmj/qgag086
URL
https://doi.org/10.1093/postmj/qgag086
Keywords Keywords not found

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