A framework of biomarkers for renal aging: a consensus statement by the Aging Biomarker Consortium
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ID: 320863
2026
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Abstract
Abstract Renal aging involves structural and functional kidney decline (reduced size/nephrons, glomerulosclerosis, tubular atrophy, functional loss) and is an independent risk factor for kidney and systemic degenerative diseases. On May 16, 2025, the Aging Biomarker Consortium (ABC) convened an expert consensus meeting in Shanghai, proposing a multidimensional biomarker framework: functional (eGFR, renal blood flow), structural (renal volume loss), and humoral (Klotho, NT-proBNP, SASP factors). The consensus also supports machine-learning models for biological age assessment and calls for multi-center cohorts and translational collaboration to improve elderly kidney health.
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| Authors | Xi Zhang, Anqun Chen, Linli Lv, Liang Ma, Yan Zheng, Beibei Ma, Ziying Zhong, Yaobin Jing, Aiming Qiu, 邵云侠, Weiqi Zhang, Jun Cen, Lili Zhou, W X Chen, C Zhang, Jian Li, J J Chen, Baoxue Yang, Ying Liu, Jing Qu, Fan Yi, Jinghong Zhao, B Liu, Xiong Z. Ruan, Lu Lm, Feng Zheng, Gai Liu, Pei Gt, Jing Nie, Youfei Guan |
| Journal | Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians |
| Year | 2026 |
| DOI |
10.1093/lifemedi/lnag026
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| Keywords | Keywords not found |
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