Frailty Status and Outcomes in Patients with Acute Coronary Syndrome Undergoing Percutaneous Coronary Intervention: a multicentre retrospective cohort study
Clicks: 8
ID: 320111
2026
Article Quality & Performance Metrics
Overall Quality
Not rated
Combines reader engagement with the AI quality analysis. This
article has not been analysed, so there is no overall score —
reader engagement is measured and shown alongside.
Reader Engagement
Steady Performance
2.1
/100
8 views
0 readers
AI Quality Assessment
Not analyzed
Readership in this journal
SteadyRanked #25 of 45 articles by views in european journal of cardiovascular nursing : journal of the working group on cardiovascular nursing of the european society of cardiology
Most read
Least read
Bar heights use a square-root scale.
Mint this article as an NFT
Not yet mintedCreate a permanent, verifiable on-chain record of this article on the Scimatic Network. The NFT is held in your Journament account, and you can withdraw it to your own wallet at any time.
5
SUSD
one-off · no wallet required
Abstract
AIM: Frailty is increasingly recognised as an age-independent predictor of adverse outcomes in cardiovascular disease, yet it is rarely assessed in acute coronary syndrome (ACS) due to practical limitations. This study examined the prognostic significance of frailty, assessed using a laboratory-based frailty index (FI-Lab), in patients with ACS undergoing percutaneous coronary intervention (PCI). METHODS AND RESULTS: We conducted a multicentre retrospective cohort study across five Korean hospitals using the Observational Medical Outcomes Partnership Common Data Model. Adult patients (≥18 years) who underwent PCI for ACS were included. Frailty status was determined as FI-Lab ≥ 0.4, calculated as the proportion of deficits across 28 routine laboratory variables, with inclusion restricted to patients having at least 70% of laboratory values available. Propensity score matching (1:1) and cox proportional hazards regression were employed to examine the relationships between frailty and clinical outcomes including recurrent acute myocardial infarction, hospital readmissions, and all-cause mortality. Of 5,405 patients, 25.2% were classified as frail. After matching, 929 pairs were analysed. Frailty was significantly associated with hospital readmission (HR 1.946; 95% CI 1.635-2.316) and all-cause mortality (HR 3.675; 95% CI 2.680-5.038), but not with recurrent AMI (HR 0.995; 95% CI 0.854-1.160). Subgroup analyses confirmed consistent associations across age and sex, with robust links to mortality in patients ≥65 years. CONCLUSION: Frailty, as assessed by FI-Lab, independently predicted hospital readmission and mortality after PCI in patients with ACS. Automated, laboratory-based frailty screening is feasible in acute settings and supports its integration into cardiovascular nursing for early risk stratification and personalised care.
| Reference Key |
openalex_W7167585664
Use this key to autocite in the manuscript while using
SciMatic Manuscript Manager or Thesis Manager
|
|---|---|
| Authors | Sujin Gan, Eun Ji Seo, Sang Youl Rhee, Won‐Woo Seo, Woo Jin Kim, Hang A Park, Rae Woong Park, Sun Hyoung Bae |
| Journal | european journal of cardiovascular nursing : journal of the working group on cardiovascular nursing of the european society of cardiology |
| Year | 2026 |
| DOI |
10.1093/eurjcn/zvag162
|
| URL | |
| Keywords | Keywords not found |
Citations
No citations found. To add a citation, contact the admin at info@scimatic.org
Comments
No comments yet. Be the first to comment on this article.