Bacteriostatic activity of a perfluorooctyl bromide emulsion and its interaction with antibiotics against selected bacterial strains in vitro

Clicks: 1
ID: 319949
2026
Free PDF
Article Quality & Performance Metrics
Overall Quality
Not rated
Combines reader engagement with the AI quality analysis. This article has not been analysed, so there is no overall score — reader engagement is measured and shown alongside.
AI Quality Assessment
Not analyzed
Readership in this journal

Ranked #106 of 172 articles by views in Journal of applied microbiology

Most read Least read

Bar heights use a square-root scale. Only the 120 most-read articles are drawn; the journal has 172 in total.

Mint this article as an NFT
Not yet minted

Create a permanent, verifiable on-chain record of this article on the Scimatic Network. The NFT is held in your Journament account, and you can withdraw it to your own wallet at any time.

5 SUSD one-off · no wallet required
Sign in to mint
Abstract
AIMS: Antibiotic resistance is an increasing global public health concern. Perfluorooctyl bromide (PFOB) has demonstrated in-vitro bacteriostatic activity against Pseudomonas aeruginosa, but it is unknown whether this effect is maintained when PFOB is emulsified (PFOBe). This study aimed to evaluate the effect of PFOBe on the growth of antibiotic-resistant strains of P. aeruginosa, Staphylococcus aureus, and Klebsiella pneumoniae. METHODS AND RESULTS: Time-kill assays were performed to evaluate the activity of meropenem, gentamicin, oxacillin, PFOBe, and antibiotic-PFOBe combinations against resistant strains (K. pneumoniae ATCC BAA-2814, P. aeruginosa CeMoP 501, and S. aureus ATCC 33591) and antibiotic-susceptible strains (K. pneumoniae ATCC 700603, P. aeruginosa ATCC 27853, and S. aureus ATCC 25923). Morphological changes were assessed using scanning electron microscopy. PFOBe showed bacteriostatic activity against all tested strains and a limited enhancement of the antibiotics when combined. Structural alterations in bacterial cell walls were observed depending on the strain and treatment combination. CONCLUSIONS: PFOBe exhibits bacteriostatic activity and enhances against both resistant and susceptible bacterial strains, suggesting its potential as an adjuvant antimicrobial strategy.
Reference Key
openalex_W7167726602 Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Fredy Leonardo Carreño Hernández, Maritza Torres, Jairo Gaitán, L T Moya, Heydys Martinez, Nicolás Rojas, Juan Carlos Briceño Triana, Adriana Marcela Celis Ramírez
Journal Journal of applied microbiology
Year 2026
DOI
10.1093/jambio/lxag170
URL
https://doi.org/10.1093/jambio/lxag170
Keywords Keywords not found

Citations

No citations found. To add a citation, contact the admin at info@scimatic.org

Comments

No comments yet. Be the first to comment on this article.