Genetic basis of R-phase H:z27 antigen expression and phylogenetic relationships of Salmonella enterica serovar Senftenberg

Clicks: 10
ID: 319575
2026
Free PDF
Article Quality & Performance Metrics
Overall Quality
Not rated
Combines reader engagement with the AI quality analysis. This article has not been analysed, so there is no overall score — reader engagement is measured and shown alongside.
AI Quality Assessment
Not analyzed
Readership in this journal
Emerging

Ranked #177 of 212 articles by views in FEMS microbiology letters

Most read Least read

Bar heights use a square-root scale. Only the 120 most-read articles are drawn; the journal has 212 in total.

Mint this article as an NFT
Not yet minted

Create a permanent, verifiable on-chain record of this article on the Scimatic Network. The NFT is held in your Journament account, and you can withdraw it to your own wallet at any time.

5 SUSD one-off · no wallet required
Sign in to mint
Abstract
Abstract Salmonella enterica serovar Senftenberg (S. Senftenberg) is one of the most common serovars isolated from various animals and humans. According to the White–Kauffmann–Le Minor scheme, its antigenic formula is defined as 1,3,19:g,[s],t:–, whereas 1,3,19:z27:– was formerly designated as serovar Simsbury but later excluded due to interconvertibility with Senftenberg. The H:z27 antigen is now recognized as an R-phase H antigen of S. Senftenberg. To clarify the genetic basis of H:z27 expression, we determined whole-genome sequences of H:z27-expressing isolates. These isolates belonged to sequence type (ST) 185 and harbored a horizontally acquired chromosomal locus containing fljB and fljA homologues, predicted to encode a flagellin and a translational repressor of fliC mRNA, respectively. Deletion of this locus resulted in expression of the H:g,s,t antigen instead of H:z27, as confirmed by serotyping and Western blot analysis. Bayesian temporal phylogenetic analysis suggested that the ST185 lineage acquired this locus around 1871 (95% highest posterior density: 1785–1934).
Reference Key
openalex_W7167243674 Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Chieko Kato, Takahiro OCHIAI, Yuta Ohno, Ikuo Uchida, Nobuo Arai, Hidemasa Izumiya, Tetsuya Ikeda, Masahiro Kusumoto, Masato Akiba
Journal FEMS microbiology letters
Year 2026
DOI
10.1093/femsle/fnag076
URL
https://doi.org/10.1093/femsle/fnag076
Keywords Keywords not found

Citations

No citations found. To add a citation, contact the admin at info@scimatic.org

Comments

No comments yet. Be the first to comment on this article.