Lactiplantibacillus plantarum LSC3 attenuates anaphylactic response in a murine model of food allergy
Clicks: 3
ID: 319425
2026
Article Quality & Performance Metrics
Overall Quality
Not rated
Combines reader engagement with the AI quality analysis. This
article has not been analysed, so there is no overall score —
reader engagement is measured and shown alongside.
Reader Engagement
Steady Performance
0.6
/100
3 views
2 readers
AI Quality Assessment
Not analyzed
Readership in this journal
SteadyRanked #95 of 174 articles by views in Journal of applied microbiology
Most read
Least read
Bar heights use a square-root scale. Only the 120 most-read articles are drawn; the journal has 174 in total.
Mint this article as an NFT
Not yet mintedCreate a permanent, verifiable on-chain record of this article on the Scimatic Network. The NFT is held in your Journament account, and you can withdraw it to your own wallet at any time.
5
SUSD
one-off · no wallet required
Abstract
Abstract Aims The present study aims to evaluate the impact of Lactiplantibacillus plantarum LSC3, previously isolated from the stool of an Algerian breastfed infant, on the development of allergic responses to milk proteins in BALB/c mice. Methods and results BALB/c mice were given orally Lactiplantibacillus plantarum LSC3 and sensitized to β-lactoglobulin according to a food allergy protocol. The results show that oral administration of L. plantarum LSC3 induced a significant decrease in the serum levels of anti β-lactoglobulin IgG and IgE. In addition, oral administration of L. plantarum LSC3 also appears to significantly decrease anaphylactic response ex vivo by reducing short circuit current (Isc) and epithelial conductance (G). Moreover, L. plantarum LSC3 attenuated clinical manifestations induced by the in vivo β-Lg challenge test and protected intestinal morphology from β-Lg-induced tissue alterations. Conclusion These findings reveal that L. plantarum LSC3 exerts immunomodulatory properties, probably through the modulation of systemic and intestinal immune responses, Significance and Impact of the Study These data suggest that L. plantarum LSC3 may therefore represent a promising probiotic candidate in cow’s milk allergy prevention strategies through it’s immunomodulatory properties.
| Reference Key |
openalex_W7167031317
Use this key to autocite in the manuscript while using
SciMatic Manuscript Manager or Thesis Manager
|
|---|---|
| Authors | C. Gheziel, Wafaa Dib, Sarra Dali, Hadda‐Imene Ouzari, Daniela Fiocco, Giuseppe Spano, Omar Kheroua, Djamel Saïdi, S. Addou, H. Kaddouri |
| Journal | Journal of applied microbiology |
| Year | 2026 |
| DOI |
10.1093/jambio/lxag155
|
| URL | |
| Keywords | Keywords not found |
Citations
No citations found. To add a citation, contact the admin at info@scimatic.org
Comments
No comments yet. Be the first to comment on this article.