Five-year Patient-reported Outcomes Following Primary Breast Augmentation With Polyurethane-coated Implants: Development and Preliminary Validation of a Device-specific Instrument

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2026
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Abstract
Abstract Background Long-term patient-reported outcomes after primary aesthetic breast augmentation remain incompletely characterized, particularly in cohorts receiving polyurethane-coated implants. Although validated generic instruments are widely used, device-specific patient perception may not be fully captured by broader outcome measures. Objectives To evaluate five-year patient-reported outcomes following primary breast augmentation with polyurethane-coated implants and to develop and preliminarily validate a device-specific patient-reported outcome instrument. Methods A retrospective cohort study was conducted including 110 consecutive patients who underwent primary aesthetic breast augmentation with polyurethane-coated implants. At a mean follow-up of 5.2 ± 0.8 years, patients completed a 15-item polyurethane implant–specific patient-reported outcome instrument (PU-PRO) assessing Perception, Aesthetic Satisfaction, and Postoperative Experience. Psychometric evaluation included content validity assessment, internal consistency analysis, exploratory factor analysis, and test–retest reliability over an 8-month interval using intraclass correlation coefficients (ICC). Results Ninety-nine patients (90%) completed the 5-year assessment, and 87 (88%) completed the 8-month reassessment. Mean scores (0–100 scale) were 81.3 ± 12.8 for Perception, 84.5 ± 11.9 for Satisfaction, and 78.2 ± 14.3 for Experience. One patient (1%) reported clinically evident rippling, and no revision surgeries occurred during follow-up. Cronbach’s alpha ranged from 0.84 to 0.91 across domains. Exploratory factor analysis supported a three-factor structure explaining 68% of total variance. ICC values ranged from 0.88 to 0.93, demonstrating high temporal stability. Conclusions Primary breast augmentation with polyurethane-coated implants demonstrated sustained high levels of patient-reported satisfaction at five-year follow-up in this cohort. The PU-PRO instrument showed preliminary evidence of reliability and construct validity. Further prospective studies incorporating validated comparative instruments are warranted.
Reference Key
openalex_W7166010214 Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Sergio Burciaga Soto, Norman Alejandro Rendón Mejía
Journal Aesthetic surgery journal
Year 2026
DOI
10.1093/asj/sjag129
URL
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