800 million years of co-evolution in the green plant lineage – the case of LEUNIG and SEUSS transcriptional co-regulators

Clicks: 3
ID: 318498
2026
Free PDF
Article Quality & Performance Metrics
Overall Quality
Not rated
Combines reader engagement with the AI quality analysis. This article has not been analysed, so there is no overall score — reader engagement is measured and shown alongside.
AI Quality Assessment
Not analyzed
Readership in this journal
Emerging

Ranked #212 of 245 articles by views in molecular biology and evolution

Most read Least read

Bar heights use a square-root scale. Only the 120 most-read articles are drawn; the journal has 245 in total.

Mint this article as an NFT
Not yet minted

Create a permanent, verifiable on-chain record of this article on the Scimatic Network. The NFT is held in your Journament account, and you can withdraw it to your own wallet at any time.

5 SUSD one-off · no wallet required
Sign in to mint
Abstract
The evolution of land plants has involved significant restructuring and expansion of gene networks responsible for developmental processes, leading to the emergence of new gene expression and protein interaction patterns. The LEUNIG (LUG) and SEUSS (SEU) families of transcriptional co-regulators play crucial roles in angiosperm sexual reproduction, and in developmental and environmental response pathways. These proteins often function together in widely pleiotropic actions and are central members of larger transcription-regulating complexes, interacting with various proteins, such as floral homeotic MADS-box transcription factors. However, the origins and evolution of interaction networks of these gene families remain poorly understood. To systematically address this knowledge gap, we conducted a comprehensive analysis integrating phylogeny reconstruction, protein domain analysis, and protein interaction studies across a broad range of streptophyte algae and land plants. Our findings demonstrate that the LUG and SEU genes have existed for at least 800 million years, with specific domains remaining nearly invariant. Protein interaction analyses reveal that LUG- and SEU-like proteins physically interact in streptophyte algae and across all land plant lineages. Notably, the origin of their interactions with MADS-box proteins also dates to at least the streptophyte algae, highlighting the ancient and conserved roles of LUG and SEU proteins as essential components of transcriptional regulation and hubs for protein interactions. Our analysis reveals insights into the ancient origins and conserved roles of LUG and SEU family members in transcriptional regulation in algal and land plant lineages.
Reference Key
openalex_W7165662833 Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Julian Garrecht, Clemens Rössner, Vishnu Narayanan Suma Sreechakram, Qi Li, Sigurd Braun, John F. Golz, Annette Becker
Journal molecular biology and evolution
Year 2026
DOI
10.1093/molbev/msag154
URL
https://doi.org/10.1093/molbev/msag154
Keywords Keywords not found

Citations

No citations found. To add a citation, contact the admin at info@scimatic.org

Comments

No comments yet. Be the first to comment on this article.