Night-to-Night Sleep Duration and Wake-Anchored Glycaemia: Associations with Continuous Glucose Monitoring in Free-Living Adolescents
Clicks: 2
ID: 317735
2026
Article Quality & Performance Metrics
Overall Quality
Not rated
Combines reader engagement with the AI quality analysis. This
article has not been analysed, so there is no overall score —
reader engagement is measured and shown alongside.
Reader Engagement
Steady Performance
0.3
/100
2 views
1 readers
AI Quality Assessment
Not analyzed
Readership in this journal
SteadyRanked #184 of 192 articles by views in Sleep & breathing = Schlaf & Atmung
Most read
Least read
Bar heights use a square-root scale. Only the 120 most-read articles are drawn; the journal has 192 in total.
Mint this article as an NFT
Not yet mintedCreate a permanent, verifiable on-chain record of this article on the Scimatic Network. The NFT is held in your Journament account, and you can withdraw it to your own wallet at any time.
5
SUSD
one-off · no wallet required
Abstract
Abstract Study Objectives Sleep duration influences metabolic health, but the impact of daily sleep variation on next-day glycaemia in healthy individuals under real-world conditions is poorly understood. Materials and methods We studied 206 adolescents (18 years) from the Copenhagen Prospective Studies on Asthma in Childhood 2000 (COPSAC2000) cohort with 2245 person-days of overlapping accelerometer-derived sleep and continuous glucose monitoring (CGM) recordings (median 13 days, IQR 9-13). Sleep duration was assessed using wrist-worn accelerometry, and glycaemic concentration, variability, and risk indices were derived from CGM during the accelerometer-defined waking period. Associations were examined using linear mixed-effects models adjusted for sociodemographic, behavioural, circadian, and cardiometabolic factors, with random effects of individuals across repeated days. Results Each additional hour of sleep was associated with higher next-day glycaemic concentration (median β 0.39 mg/dL [0.15, 0.63], p = .002), lower variability (standard deviation (SD) mg/dL β -0.12 [-0.23, -0.01], p = .036), and reduced deviation risk (Average Daily Risk Range (ADRR), indicating lower risk of extreme glucose excursions; β -0.27 [-0.43, -0.10], p = .002). Within-person deviations in sleep predicted next-day glycaemic concentration and deviation risk, whereas habitual between-person differences were more strongly associated with variability. Higher daytime glycaemic variability predicted shorter subsequent sleep (β -0.11 h [-0.18, -0.05], p < 0.001). The early-morning pre-wake glucose rise partly mediated the link between longer sleep and higher next-day median glucose (indirect effect 5.0%, p = 0.036). Conclusions These findings indicate dynamic, bidirectional coupling between sleep and glucose regulation in free-living adolescents, with longer sleep associated with lower next-day glycaemic variability and reduced risk of extreme glucose excursions.
| Reference Key |
openalex_W7165207475
Use this key to autocite in the manuscript while using
SciMatic Manuscript Manager or Thesis Manager
|
|---|---|
| Authors | David Horner, Kristen Evensen, Zhi Ye, Marie Jahn, Kaare Tranæs, Jonathan Thorsen, Thomas R. Wood, Kristi Storoschuk, Nanette Mol Debes, Jannet Svensson, Jordi Merino, Rikke Beck Jensen, Thomas A Jepps, David S. Ludwig, Ruth J F Loos, Klaus Bønnelykke, Rebecca Vinding, M S Rasmussen |
| Journal | Sleep & breathing = Schlaf & Atmung |
| Year | 2026 |
| DOI |
10.1093/sleep/zsag158
|
| URL | |
| Keywords | Keywords not found |
Citations
No citations found. To add a citation, contact the admin at info@scimatic.org
Comments
No comments yet. Be the first to comment on this article.