Total synthesis and stability analysis of natural diacyl-type tuliposides and their non-natural isomers

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ID: 316440
2026
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Abstract
Abstract Tuliposides (Pos), major secondary metabolites in tulip, are classified into monoacyl- and diacyl-type compounds. Herein, we report the first total synthesis of naturally occurring diacyl-type PosD and PosF and their isomers diOH-PosD and isoPosF, respectively, from D-glucose in five steps. Under neutral conditions, the non-natural Pos isomers were significantly less stable than their natural counterparts.
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openalex_W7164025940 Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Yasuo Kato, Kaito Sano, Taiji Nomura
Journal bioscience biotechnology and biochemistry
Year 2026
DOI
10.1093/bbb/zbag085
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