Identification of the biosynthetic gene cluster for PF1451A: Implications for untapped peptide biosynthetic pathways widely distributed in fungi
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ID: 314530
2026
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Abstract
The biosynthetic gene cluster for PF1451A (1), a potent fungicidal peptide, was identified, showing 1 is a member of ribosomally synthesized and post-translationally modified peptides of fungal origin. Notably, a hypothetical protein belonging to IPR053008 family was involved in the desaturation of valine residue. Bioinformatic analysis demonstrated wide distribution of similar proteins in the fungal genomes.
| Reference Key |
openalex_W7161982691
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|---|---|
| Authors | Genki Hibi, Taro Ozaki, Riku Sugimoto, Yohei Morishita, Teigo Asai |
| Journal | bioscience biotechnology and biochemistry |
| Year | 2026 |
| DOI |
10.1093/bbb/zbag074
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| URL | |
| Keywords | Keywords not found |
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