Intimate encapsulation of non-planar electrodes via a viscoplastic interlayer

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ID: 314237
2026
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Abstract
Abstract Implantable electronics often adopt non-planar electrodes to resolve the conflict between conductivity and deformability. Encapsulation of these electrodes becomes a critical challenge for conventional elastic seals due to the elastic-contact-induced interfacial voids and consequential fluid ingress. Here, we present a viscoplastic interlayer that can adapt to the three-dimensional structures of non-planar electrodes, resulting in intimate contact and hermetic encapsulation. This interlayer is a polymeric composite that consists of a long-chain polyisobutylene as the matrix, a short-chain polyisobutylene as the plasticizer, and maleic anhydride-grafted polypropylene as the foreign domains. Its viscoplasticity originates from the chain slippage and permanent disentanglement of the long-chain polyisobutylene, promoted by the plasticizers and confining domains, respectively. When synergized with covalent bonding, the interlayer derives defect-free interfaces between the sealing elastomer and various non-planar electrodes, such as microwires, micropillars, and serpentine electrodes. This intimate encapsulation stabilizes the signal-to-noise ratio of an electromechanical device for 50 weeks in acidic, neutral, and alkaline solutions and extends the in vivo duration of signal fidelity for stretchable bioelectronics to a record 45 weeks. This viscoplastic interlayer provides fruitful implications for improving the long-term stability of implantable bioelectronics.
Reference Key
openalex_W7161837725 Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Liqian Liu, Xinyue Xiang, Yinglin Zhi, Guoli Chen, Yan Shao, Rui Xia, Daohang Cai, Huiping Wu, Yuda Chen, Jingjia Li, Fuzeng Ren, S Zhang, Chuanfei Guo, Yanhao Yu
Journal national science review
Year 2026
DOI
10.1093/nsr/nwag297
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