A novel metronidazole-degrading bacterium Sphingopyxis sp. K5: isolation, characterization, and application potential in soil and wastewater remediation
Clicks: 3
ID: 313396
2026
Article Quality & Performance Metrics
Overall Quality
Not rated
Combines reader engagement with the AI quality analysis. This
article has not been analysed, so there is no overall score —
reader engagement is measured and shown alongside.
Reader Engagement
Emerging Content
0.6
/100
3 views
2 readers
AI Quality Assessment
Not analyzed
Readership in this journal
EmergingRanked #197 of 208 articles by views in FEMS microbiology letters
Most read
Least read
Bar heights use a square-root scale. Only the 120 most-read articles are drawn; the journal has 208 in total.
Mint this article as an NFT
Not yet mintedCreate a permanent, verifiable on-chain record of this article on the Scimatic Network. The NFT is held in your Journament account, and you can withdraw it to your own wallet at any time.
5
SUSD
one-off · no wallet required
Abstract
Metronidazole is a widely used nitroimidazole antibiotic in clinical practice. Following its widespread use, it enters the environment via medical wastewater, posing a potential risk of toxicity to ecosystems and living organisms. Microbial degradation is an efficient method of accurately eliminating target pollutants from the environment. Here, a metronidazole degrader, Sphingopyxis sp. K5, was isolated from medical wastewater sludge. Strain K5 could degrade 58.7 μM metronidazole after 4 days of incubation with an initial OD600 of 1.5. The optimal degradation conditions were 35°C and pH 8.0, and the strain exhibited stable degradation efficiency on high metronidazole concentrations (100-500 μM). The supplementation of nutrients such as LB or glucose can improve degradation efficiency by 152.0% and 129.0%, respectively. Design-Expert software was used for optimization of conditions such as temperature (33.7°C), pH (8.2), and cell density of inoculation (OD600 of 1.0). The degradation of metronidazole in soil and wastewater by strain K5 proved its potential for application. Strain K5 could eliminate > 95% of 5 and 25 ppm metronidazole in soil and wastewater within 5 and 10 days, respectively. Our results characterized the degradation efficiency of metronidazole by strain K5 and provided a theoretical basis for the bioremediation of metronidazole-contaminated environments.
| Reference Key |
openalex_W7161268636
Use this key to autocite in the manuscript while using
SciMatic Manuscript Manager or Thesis Manager
|
|---|---|
| Authors | Shunyi Qian, Huayi Wang, Yuqian Liu, Jiapeng Ding, Yue Zhang, Z Zhang, Zifa Deng, Yidong Zhou |
| Journal | FEMS microbiology letters |
| Year | 2026 |
| DOI |
10.1093/femsle/fnag059
|
| URL | |
| Keywords | Keywords not found |
Citations
No citations found. To add a citation, contact the admin at info@scimatic.org
Comments
No comments yet. Be the first to comment on this article.