Analysis of the impact of urological malignant tumor surgery on child–pugh classification and prognosis in patients with liver cirrhosis
Clicks: 1
ID: 310258
2026
Article Quality & Performance Metrics
Overall Quality
Not rated
Combines reader engagement with the AI quality analysis. This
article has not been analysed, so there is no overall score —
reader engagement is measured and shown alongside.
Reader Engagement
0.0
/100
1 views
0 readers
AI Quality Assessment
Not analyzed
Readership in this journal
Ranked #427 of 490 articles by views in Frontiers in surgery
Most read
Least read
Bar heights use a square-root scale. Only the 120 most-read articles are drawn; the journal has 490 in total.
Mint this article as an NFT
Not yet mintedCreate a permanent, verifiable on-chain record of this article on the Scimatic Network. The NFT is held in your Journament account, and you can withdraw it to your own wallet at any time.
5
SUSD
one-off · no wallet required
Abstract
ObjectivePatients with liver cirrhosis often present with relative contraindications to surgery, such as impaired coagulation function and thrombocytopenia.MethodsA total of 69 patients with urinary system malignancies who underwent radical resection under general anesthesia in the urology department of our hospital between 2013 and 2025 were included in this study. A Wilcoxon rank sum test was conducted to evaluate changes in the Child–Pugh(CP) classification before and after general anesthesia in patients with urinary system malignancies complicated by liver cirrhosis. The Pearson chi-square test was employed to assess the impact of various liver cirrhosis-related factors on the likelihood of CP classification downgrade.ResultsA total of 54 patients were classified as CP grade A prior to surgery. For patients with malignant tumors of urology combined with cirrhosis, the mean CP score (P < 0.0001) increased before and after surgery. There was no statistically significant effect of various liver cirrhosis-related factors on deterioration in the CP classification (P = 0.072). Univariate and multivariate analyses demonstrated that CP classification downgrading was significantly associated with overall survival (OS) (P = 0.006), cancer-specific survival (CSS) (P = 0.028), and disease-free survival (DFS) (P = 0.039). Compared with patients with a downgraded CP classification, patients without a downgraded CP classification had a more favorable survival curve (OS, P = 0.0034; CSS, P = 0.0194; DFS, P = 0.0296).ConclusionSurgery for malignant urinary system tumors in patients with CP grades A and B is generally considered safe. However, in some cases, the procedure may result in an elevated CP score and a downgrade in classification.
| Reference Key |
imported_1768925762_696faa42cb2cb
Use this key to autocite in the manuscript while using
SciMatic Manuscript Manager or Thesis Manager
|
|---|---|
| Authors | Xue, Wenrui |
| Journal | Frontiers in surgery |
| Year | 2026 |
| DOI |
10.3389/fsurg.2025.1716296
|
| URL | |
| Keywords | Keywords not found |
Citations
No citations found. To add a citation, contact the admin at info@scimatic.org
Comments
No comments yet. Be the first to comment on this article.