Analysis of the diagnostic value of peripheral blood immune inflammatory indicators of female bladder pain syndrome
Clicks: 1
ID: 310102
2025
Article Quality & Performance Metrics
Overall Quality
Not rated
Combines reader engagement with the AI quality analysis. This
article has not been analysed, so there is no overall score —
reader engagement is measured and shown alongside.
Reader Engagement
0.0
/100
1 views
0 readers
AI Quality Assessment
Not analyzed
Readership in this journal
Ranked #290 of 490 articles by views in Frontiers in surgery
Most read
Least read
Bar heights use a square-root scale. Only the 120 most-read articles are drawn; the journal has 490 in total.
Mint this article as an NFT
Not yet mintedCreate a permanent, verifiable on-chain record of this article on the Scimatic Network. The NFT is held in your Journament account, and you can withdraw it to your own wallet at any time.
5
SUSD
one-off · no wallet required
Abstract
Introduction and hypothesisFemale bladder pain syndrome (FBPS), previously known as interstitial cystitis/bladder pain syndrome (IC/BPS). Numerous research indirectly prove that Female bladder pain syndrome (FBPS) is associated with immune-related inflammation. According to the correlation analysis between peripheral blood immune-inflammatory markers and disease diagnosis, this research further verifies the potential diagnostic value of peripheral blood inflammatory markers in FBPS.MethodA total of 149 women with bladder pain syndrome who visited the urology department of our hospital from January 2013 to December 2024 and 149 healthy controls Patients who underwent health examinations at the physical examination center of our hospital from January 2022 to January 2023 were screened. All patients' peripheral blood inflammatory markers at admission included Neutrophil-to-Lymphocyte ratio (NLR), Systemic Immune Inflammation index (SII), et al. The maximum bladder capacity (MBC) during surgery served as the bladder volume. Multivariate binary regression was used to calculate the correlation between these indicators and disease diagnosis as well as MBC. The correlation between these indicators and MBC is secondary outcomes. The optimal cut-off value for the parameters was identified using the receiver operating characteristic (ROC) curve and its area under the curve (AUC) over time.ResultsCompared with the control group, patients in the observation group demonstrated significantly higher SII, NLR, PLR, neutrophil count, whereas peripheral blood platelet count (PLT) and absolute lymphocyte count decreased, with statistically significant differences (all P < 0.05). Multivariate binary logistic regression analysis revealed increased NLR as an independent risk factor for FBPS. Compared with the normal bladder capacity group, patients with small bladder capacity demonstrated significantly lower SII, PLR, PLT, with statistically significant differences (all P < 0.05). Multivariate binary logistic regression analysis revealed decreased PLT as an independent risk factor for reduced bladder capacity.ConclusionPeripheral blood inflammation indicators can be employed as an auxiliary diagnostic standard for FPBS, and NLR can be used as an independent diagnostic indicator for FBPS. However, further prospective studies are warranted to identify the causal relationship of these indicators with patient symptoms.
| Reference Key |
imported_1768922114_696f9c022bcfc
Use this key to autocite in the manuscript while using
SciMatic Manuscript Manager or Thesis Manager
|
|---|---|
| Authors | Hu, Hailong |
| Journal | Frontiers in surgery |
| Year | 2025 |
| DOI |
10.3389/fsurg.2025.1685098
|
| URL | |
| Keywords | Keywords not found |
Citations
No citations found. To add a citation, contact the admin at info@scimatic.org
Comments
No comments yet. Be the first to comment on this article.