Impact of the Body Mass Index on the Intensive Care Outcome of (Poly-)Traumatized Patients

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Abstract
Purpose: The increasing prevalence of obesity poses significant challenges to intensive care medicine, particularly in trauma care. The "obesity paradox", suggesting enhanced survival in overweight individuals, remains controversial. The study aimed to investigate the association between Body Mass Index and intensive care outcomes in severely injured patients. Methods: A retrospective matched 1:2:1 set analysis with n = 192 / 384 / 192 patients was conducted using data from the TraumaRegister DGU®. A total of 5766 patients admitted to intensive care were included and categorized into three BMI groups: underweight (≤20 kg/m²), normal weight/overweight (20.1–29.9 kg/m²), and obese (≥30 kg/m²). The application of World Health Organization classification was precluded on statistical grounds. A subgroup of polytraumatized patients (n = 272) was separately analyzed. Outcomes included the duration of mechanical ventilation, ICU stay, organ failure, and in-hospital mortality. Results: BMI was positively associated with organ failure, especially cardiac (p = 0.001) and pulmonary failure (p = 0.001). The mortality rate was twice as high for obese patients as for underweight patients in the matched cohort (Group III: 10.4%; Group I: 5.2%; p (linear trend) = 0.025). Ventilation time increased significantly with higher BMI (p = 0.012). Conclusion: In this cohort, there was an absence of evidence to support the notion of an "obesity paradox". Overweight and obesity were not associated with improved survival and were instead linked to less favorable intensive care outcomes following severe trauma, although absolute differences in mortality were modest. Trial Registration: ID 2014-021.
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imported_1768914886_696f7fc6029e5 Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Gerbershagen, Mark Ulrich
Journal Frontiers in surgery
Year Year not found
DOI
10.3389/fanes.2026.1740319
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