First evidence of murid gammaherpesvirus 4 (MHV-68) virus in the blood of oncological patients

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ID: 309982
2025
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Ranked #299 of 490 articles by views in Frontiers in surgery

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Abstract
Murid gammaherpesvirus 4 (prototype strain MHV-68) is a natural pathogen of murid rodents that is able to transform lymphocytes and induce lymphoproliferative diseases and tumor transformation in their host cells. Considering that this virus can infect and multiply in various human cell lines, we think it could also play an important role in the pathogenesis of some human types of cancer. We investigated and confirmed the presence of the replication and transcription activator rta (ORF 50) from MHV-68 virus in four peripheral blood samples from patients with lymphomas and gliomas.
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imported_1768907726_696f63ceb15fe Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Kabát, Peter
Journal Frontiers in surgery
Year 2025
DOI
10.3389/av.2025.14168
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