Preoperative assessment of prognostic factors in rectal cancer using high-resolution magnetic resonance imaging

Clicks: 2
ID: 307673
2003
Free PDF
Article Quality & Performance Metrics
Overall Quality
Not rated
Combines reader engagement with the AI quality analysis. This article has not been analysed, so there is no overall score — reader engagement is measured and shown alongside.
AI Quality Assessment
Not analyzed
Readership in this journal
Emerging

Ranked #76 of 432 articles by views in the british journal of surgery

Most read Least read

Bar heights use a square-root scale. Only the 120 most-read articles are drawn; the journal has 432 in total.

Mint this article as an NFT
Not yet minted

Create a permanent, verifiable on-chain record of this article on the Scimatic Network. The NFT is held in your Journament account, and you can withdraw it to your own wallet at any time.

5 SUSD one-off · no wallet required
Sign in to mint
Abstract
Abstract Background The aim was to determine the accuracy of preoperative magnetic resonance imaging (MRI) in the evaluation of pathological prognostic factors that influence local recurrence and survival in rectal cancer. Methods Ninety-eight patients undergoing total mesorectal excision for biopsy-proven rectal cancer were assessed prospectively using high-resolution MRI for tumour (T) and nodal (N) staging using the tumour node metastasis classification, depth of extramural tumour spread, the presence or absence of extramural venous invasion, a threatened circumferential resection margin and serosal involvement at or above the peritoneal reflection. Preoperative magnetic resonance assessment of these prognostic factors was compared with histopathological findings in carefully matched whole-mount sections of the resection specimen. Results There was 94 per cent weighted agreement (weighted κ = 0·67) between MRI and pathology assessment of T stage. Agreement between MRI and histological assessment of nodal status was 85 per cent (κ = 0·68). Although involvement of small veins by tumour was not discernible using MRI, large (calibre greater than 3 mm) extramural venous invasion was identified correctly in 15 of 18 patients (κ = 0·64). MRI predicted circumferential resection margin involvement with 92 per cent agreement (κ = 0·81). Seven of nine patients with peritoneal perforation by tumour (stage T4) were identified correctly using MRI. Conclusion High-resolution MRI of the rectum allows preoperative identification of important surgical and pathological prognostic risk factors. This may allow both better selection and assessment of patients undergoing preoperative therapy.
Reference Key
openalex_W2107982027 Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Gina Brown, A G Radcliffe, Robert G. Newcombe, N S Dallimore, Michael W. Bourne, Geraint T. Williams
Journal the british journal of surgery
Year 2003
DOI
10.1002/bjs.4034
URL
https://doi.org/10.1002/bjs.4034
Keywords Keywords not found

Citations

No citations found. To add a citation, contact the admin at info@scimatic.org

Comments

No comments yet. Be the first to comment on this article.