Rates of formation and thermal stabilities of RNA:DNA and DNA:DNA duplexes at high concentrations of formamide

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ID: 307671
1977
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Abstract
The thermal stabilities of RNA:DNA hybrids are substantially greater than those of DNA:DNA duplexes in aqueous electrolyte solutions containing high concentrations of formamide. Association rates to form DNA:DNA duplexes and DNA:RNA hybrids have been measured in these solvents. There is a temperature range in which DNA:DNA rates are negligible and RNA:DNA rates close to optimal.
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openalex_W2052830722 Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors James W. Casey, Norman Davidson
Journal Nucleic Acids Research
Year 1977
DOI
10.1093/nar/4.5.1539
URL
https://doi.org/10.1093/nar/4.5.1539
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