EcoCyc: a comprehensive database resource for Escherichia coli

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ID: 306391
2004
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Abstract
The EcoCyc database ( http://EcoCyc.org/ ) is a comprehensive source of information on the biology of the prototypical model organism Escherichia coli K12. The mission for EcoCyc is to contain both computable descriptions of, and detailed comments describing, all genes, proteins, pathways and molecular interactions in E.coli . Through ongoing manual curation, extensive information such as summary comments, regulatory information, literature citations and evidence types has been extracted from 8862 publications and added to Version 8.5 of the EcoCyc database. The EcoCyc database can be accessed through a World Wide Web interface, while the downloadable Pathway Tools software and data files enable computational exploration of the data and provide enhanced querying capabilities that web interfaces cannot support. For example, EcoCyc contains carefully curated information that can be used as training sets for bioinformatics prediction of entities such as promoters, operons, genetic networks, transcription factor binding sites, metabolic pathways, functionally related genes, protein complexes and protein–ligand interactions.
Reference Key
openalex_W2108078368 Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Ingrid M. Keseler, Julio Collado‐Vides, Socorro Gama‐Castro, John Ingraham, Suzanne Paley, Ian T. Paulsen, Martín Peralta-Gil, Peter D. Karp
Journal Nucleic Acids Research
Year 2004
DOI
10.1093/nar/gki108
URL
https://doi.org/10.1093/nar/gki108
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