missMethyl: an R package for analyzing data from Illumina’s HumanMethylation450 platform

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ID: 306296
2015
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Abstract
Abstract Summary: DNA methylation is one of the most commonly studied epigenetic modifications due to its role in both disease and development. The Illumina HumanMethylation450 BeadChip is a cost-effective way to profile >450 000 CpGs across the human genome, making it a popular platform for profiling DNA methylation. Here we introduce missMethyl, an R package with a suite of tools for performing normalization, removal of unwanted variation in differential methylation analysis, differential variability testing and gene set analysis for the 450K array. Availability and implementation: missMethyl is an R package available from the Bioconductor project at www.bioconductor.org. Contact: alicia.oshlack@mcri.edu.au Supplementary information: Supplementary data are available at Bioinformatics online.
Reference Key
openalex_W2261451134 Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Belinda Phipson, Jovana Maksimovic, Alicia Oshlack
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Journal BMC Bioinformatics
Year 2015
DOI
10.1093/bioinformatics/btv560
URL
https://doi.org/10.1093/bioinformatics/btv560
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