missMethyl: an R package for analyzing data from Illumina’s HumanMethylation450 platform

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ID: 306296
2015
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Abstract
Abstract Summary: DNA methylation is one of the most commonly studied epigenetic modifications due to its role in both disease and development. The Illumina HumanMethylation450 BeadChip is a cost-effective way to profile >450 000 CpGs across the human genome, making it a popular platform for profiling DNA methylation. Here we introduce missMethyl, an R package with a suite of tools for performing normalization, removal of unwanted variation in differential methylation analysis, differential variability testing and gene set analysis for the 450K array. Availability and implementation: missMethyl is an R package available from the Bioconductor project at www.bioconductor.org. Contact: alicia.oshlack@mcri.edu.au Supplementary information: Supplementary data are available at Bioinformatics online.
Reference Key
openalex_W2261451134 Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Belinda Phipson, Jovana Maksimovic, Alicia Oshlack
Journal BMC Bioinformatics
Year 2015
DOI
10.1093/bioinformatics/btv560
URL
https://doi.org/10.1093/bioinformatics/btv560
Keywords Keywords not found

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