Silver nanoparticles and polymeric medical devices: a new approach to prevention of infection?

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ID: 305171
2004
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Ranked #77 of 81 articles by views in The Journal of antimicrobial chemotherapy

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Abstract
Objectives: Implantable devices are major risk factors for hospital-acquired infection. Biomaterials coated with silver oxide or silver alloy have all been used in attempts to reduce infection, in most cases with controversial or disappointing clinical results. We have developed a completely new approach using supercritical carbon dioxide to impregnate silicone with nanoparticulate silver metal. This study aimed to evaluate the impregnated polymer for antimicrobial activity.
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Authors Franck Furno, Kelly S. Morley, Ben Wong, Barry L. Sharp, Polly L. Arnold, Steven M. Howdle, Roger Bayston, Paul D. Brown, P. Winship, Helen J. Reid
Journal The Journal of antimicrobial chemotherapy
Year 2004
DOI
10.1093/jac/dkh478
URL
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