An interactive graphics program for comparing and aligning nucleic acid and amino acid sequences

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ID: 304321
1982
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Abstract
This paper describes a computer program designed to look for similarities between pairs of nucleic or amino acid sequences. The program looks both for segments of perfect identity or for regions where, using a scoring matrix, a minimum value is exceeded. The results of comparisons are presented as a matrix which is displayed on a simple graphics terminal. Use of a graphics terminal allows the user to display the whole of the two sequences in one screenful or to home-in on regions of interest to examine them in more detail. The program is interactive and so the user can easily see the effect of changes to variables and can use inbuilt editing functions to make insertions to produce alignments of the two sequences. These aligned sequences can then be saved on disk files for further processing.
Reference Key
openalex_W1973928866 Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Rodger Staden
Journal Nucleic Acids Research
Year 1982
DOI
10.1093/nar/10.9.2951
URL
https://doi.org/10.1093/nar/10.9.2951
Keywords Keywords not found

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