Microbial carboxyl esterases: classification, properties and application in biocatalysis

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ID: 302236
2002
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Abstract
Esterases (EC 3.1.1.x) represent a diverse group of hydrolases catalyzing the cleavage and formation of ester bonds and are widely distributed in animals, plants and microorganisms. Beside lipases, a considerable number of microbial carboxyl esterases have also been discovered and overexpressed. This review summarizes their properties and classification. Special emphasis is given on their application in organic synthesis for the resolution of racemates and prostereogenic compounds. In addition, recent results for altering their properties by directed evolution are presented.
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openalex_W2166537396 Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Uwe T. Bornscheuer
Journal FEMS microbiology reviews
Year 2002
DOI
10.1111/j.1574-6976.2002.tb00599.x
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