GalaxyWEB server for protein structure prediction and refinement

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ID: 301833
2012
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Abstract
Three-dimensional protein structures provide invaluable information for understanding and regulating biological functions of proteins. The GalaxyWEB server predicts protein structure from sequence by template-based modeling and refines loop or terminus regions by ab initio modeling. This web server is based on the method tested in CASP9 (9th Critical Assessment of techniques for protein Structure Prediction) as 'Seok-server', which was assessed to be among top performing template-based modeling servers. The method generates reliable core structures from multiple templates and re-builds unreliable loops or termini by using an optimization-based refinement method. In addition to structure prediction, a user can also submit a refinement only job by providing a starting model structure and locations of loops or termini to refine. The web server can be freely accessed at http://galaxy.seoklab.org/.
Reference Key
openalex_W2080876451 Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Jin Hwan Ko, Hahnbeom Park, Lim Heo, Chaok Seok
Journal Nucleic Acids Research
Year 2012
DOI
10.1093/nar/gks493
URL
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