From head to toes: the multiple facets of Sox proteins
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ID: 301801
1999
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Abstract
Sox proteins belong to the HMG box superfamily of DNA-binding proteins and are found throughout the animal kingdom. They are involved in the regulation of such diverse developmental processes as germ layer formation, organ development and cell type specifi-cation. Hence, deletion or mutation of Sox proteins often results in developmental defects and congenital disease in humans. Sox proteins perform their function in a complex interplay with other transcription factors in a manner highly dependent on cell type and promoter context. They exhibit a remarkable crosstalk and functional redundancy among each other.
| Reference Key |
openalex_W2103619902
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|---|---|
| Authors | Michael Wegner |
| Journal | Nucleic Acids Research |
| Year | 1999 |
| DOI |
10.1093/nar/27.6.1409
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| URL | |
| Keywords | Keywords not found |
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