ChAMP: updated methylation analysis pipeline for Illumina BeadChips

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ID: 301791
2017
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Abstract
The Illumina Infinium HumanMethylationEPIC BeadChip is the new platform for high-throughput DNA methylation analysis, effectively doubling the coverage compared to the older 450 K array. Here we present a significantly updated and improved version of the Bioconductor package ChAMP, which can be used to analyze EPIC and 450k data. Many enhanced functionalities have been added, including correction for cell-type heterogeneity, network analysis and a series of interactive graphical user interfaces.ChAMP is a BioC package available from https://bioconductor.org/packages/release/bioc/html/ChAMP.html.a.teschendorff@ucl.ac.uk or s.beck@ucl.ac.uk or a.feber@ucl.ac.uk.Supplementary data are available at Bioinformatics online.
Reference Key
openalex_W2745417329 Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Yuan Tian, Tiffany Morris, Amy P. Webster, Zhen Yang, Stephan Beck, Andrew Feber, Andrew E. Teschendorff
Journal BMC Bioinformatics
Year 2017
DOI
10.1093/bioinformatics/btx513
URL
https://academic.oup.com/bioinformatics/article-pdf/33/24/3982/25168400/btx513.pdf
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