ChAMP: 450k Chip Analysis Methylation Pipeline
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ID: 301061
2013
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Abstract
Abstract The Illumina Infinium HumanMethylation450 BeadChip is a new platform for high-throughput DNA methylation analysis. Several methods for normalization and processing of these data have been published recently. Here we present an integrated analysis pipeline offering a choice of the most popular normalization methods while also introducing new methods for calling differentially methylated regions and detecting copy number aberrations. Availability and implementation: ChAMP is implemented as a Bioconductor package in R. The package and the vignette can be downloaded at bioconductor.org Contact: tiffany.morris@ucl.ac.uk
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| Reference Key |
openalex_W2136895197
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|---|---|
| Authors | Tiffany Morris, Lee M Butcher, Andrew Feber, Andrew E. Teschendorff, Ankur Chakravarthy, Tomasz K. Wojdacz, Stephan Beck |
| Journal | BMC Bioinformatics |
| Year | 2013 |
| DOI |
10.1093/bioinformatics/btt684
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| URL | |
| Keywords | Keywords not found |
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