RefSeq and LocusLink: NCBI gene-centered resources

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ID: 301040
2001
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Abstract
Thousands of genes have been painstakingly identified and characterized a few genes at a time. Many thousands more are being predicted by large scale cDNA and genomic sequencing projects, with levels of evidence ranging from supporting mRNA sequence and comparative genomics to computing ab initio models. This, coupled with the burgeoning scientific literature, makes it critical to have a comprehensive directory for genes and reference sequences for key genomes. The NCBI provides two resources, LocusLink and RefSeq, to meet these needs. LocusLink organizes information around genes to generate a central hub for accessing gene-specific information for fruit fly, human, mouse, rat and zebrafish. RefSeq provides reference sequence standards for genomes, transcripts and proteins; human, mouse and rat mRNA RefSeqs, and their corresponding proteins, are discussed here. Together, RefSeq and LocusLink provide a non-redundant view of genes and other loci to support research on genes and gene families, variation, gene expression and genome annotation. Additional information about LocusLink and RefSeq is available at http://www.ncbi.nlm.nih.gov/LocusLink/.
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openalex_W2165270659 Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Kim D. Pruitt
Journal Nucleic Acids Research
Year 2001
DOI
10.1093/nar/29.1.137
URL
https://academic.oup.com/nar/article-pdf/29/1/137/9905105/290137.pdf
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