arrayQualityMetrics—a bioconductor package for quality assessment of microarray data

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ID: 300900
2008
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Abstract
Abstract Summary:: The assessment of data quality is a major concern in microarray analysis. arrayQualityMetrics is a Bioconductor package that provides a report with diagnostic plots for one or two colour microarray data. The quality metrics assess reproducibility, identify apparent outlier arrays and compute measures of signal-to-noise ratio. The tool handles most current microarray technologies and is amenable to use in automated analysis pipelines or for automatic report generation, as well as for use by individuals. The diagnosis of quality remains, in principle, a context-dependent judgement, but our tool provides powerful, automated, objective and comprehensive instruments on which to base a decision. Availability:: arrayQualityMetrics is a free and open source package, under LGPL license, available from the Bioconductor project at www.bioconductor.org. A users guide and examples are provided with the package. Some examples of HTML reports generated by arrayQualityMetrics can be found at http://www.microarray-quality.org Contact:: audrey@ebi.ac.uk Supplementary information:: Supplementary data are available at Bioinformatics online.
Reference Key
openalex_W2159096710 Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Audrey Kauffmann, Robert Gentleman, Wolfgang Huber
Journal BMC Bioinformatics
Year 2008
DOI
10.1093/bioinformatics/btn647
URL
https://academic.oup.com/bioinformatics/article-pdf/25/3/415/16891414/btn647.pdf
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