GSCALite: a web server for gene set cancer analysis

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ID: 300650
2018
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Abstract
The availability of cancer genomic data makes it possible to analyze genes related to cancer. Cancer is usually the result of a set of genes and the signal of a single gene could be covered by background noise. Here, we present a web server named Gene Set Cancer Analysis (GSCALite) to analyze a set of genes in cancers with the following functional modules. (i) Differential expression in tumor versus normal, and the survival analysis; (ii) Genomic variations and their survival analysis; (iii) Gene expression associated cancer pathway activity; (iv) miRNA regulatory network for genes; (v) Drug sensitivity for genes; (vi) Normal tissue expression and eQTL for genes. GSCALite is a user-friendly web server for dynamic analysis and visualization of gene set in cancer and drug sensitivity correlation, which will be of broad utilities to cancer researchers.GSCALite is available on http://bioinfo.life.hust.edu.cn/web/GSCALite/.Supplementary data are available at Bioinformatics online.
Reference Key
openalex_W2804658429 Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Chunjie Liu, Feifei Hu, Meng-Xuan Xia, Leng Han, Qiong Zhang, An‐Yuan Guo
Journal BMC Bioinformatics
Year 2018
DOI
10.1093/bioinformatics/bty411
URL
https://academic.oup.com/bioinformatics/article-pdf/34/21/3771/26146888/bty411.pdf
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