FoldIndex(C): a simple tool to predict whether a given protein sequence is intrinsically unfolded
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ID: 300634
2005
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Abstract
Summary: An easy-to-use, versatile and freely available graphic web server, FoldIndex© is described: it predicts if a given protein sequence is intrinsically unfolded implementing the algorithm of Uversky and co-workers, which is based on the average residue hydrophobicity and net charge of the sequence. FoldIndex© has an error rate comparable to that of more sophisticated fold prediction methods. Sliding windows permit identification of large regions within a protein that possess folding propensities different from those of the whole protein.
| Reference Key |
openalex_W2131965976
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|---|---|
| Authors | Jaime Prilusky, Clifford E. Felder, Tzviya Zeev‐Ben‐Mordehai, Edwin H. Rydberg, Orna Man, J. Beckmann, Israel Silman, Joel L. Sussman |
| Journal | BMC Bioinformatics |
| Year | 2005 |
| DOI |
10.1093/bioinformatics/bti537
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| URL | |
| Keywords | Keywords not found |
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