Health Care Costs and Mortality Associated with Nosocomial Diarrhea Due to Clostridium difficile

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ID: 300220
2002
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Ranked #523 of 532 articles by views in Clinical infectious diseases : an official publication of the Infectious Diseases Society of America

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Abstract
A total of 271 patients were prospectively followed up to determine whether patients whose hospital stay is complicated by diarrhea due to Clostridium difficile experience differences in cost and length of stay and survival rates when compared with patients whose stay is not complicated by C. difficile–associated diarrhea. Forty patients (15%) developed nosocomial C. difficile–associated diarrhea. These patients incurred adjusted hospital costs of $3669—that is, 54% (95% confidence interval [CI], 17%–103%)—higher than patients whose course was not complicated by C. difficile–associated diarrhea. The extra length of stay attributable to C. difficile–associated diarrhea was 3.6 days (95% CI, 1.5–6.2). C. difficile–associated diarrhea was not associated with excess 3-month or 1-year mortality after adjustment for age, comorbidity, and disease severity. On the basis of the findings of this study, a conservative estimate of the cost of this disease in the United States exceeds $1.1 billion per year.
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Authors Lorraine Kyne, M. B. Hamel, Raju Polavaram, Ciarán P. Kelly
Journal Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
Year 2002
DOI
10.1086/338260
URL
https://doi.org/10.1086/338260
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