CluePedia Cytoscape plugin: pathway insights using integrated experimental and in silico data

Clicks: 1
ID: 298903
2013
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Abstract
Abstract Summary: The CluePedia Cytoscape plugin is a search tool for new markers potentially associated to pathways. CluePedia calculates linear and non-linear statistical dependencies from experimental data. Genes, proteins and miRNAs can be connected based on in silico and/or experimental information and integrated into a ClueGO network of terms/pathways. Interrelations within each pathway can be investigated, and new potential associations may be revealed through gene/protein/miRNA enrichments. A pathway-like visualization can be created using the Cerebral plugin layout. Combining all these features is essential for data interpretation and the generation of new hypotheses. The CluePedia Cytoscape plugin is user-friendly and has an expressive and intuitive visualization. Availability: http://www.ici.upmc.fr/cluepedia/ and via the Cytoscape plugin manager. The user manual is available at the CluePedia website. Contact: bernhard.mlecnik@crc.jussieu.fr or jerome.galon@crc.jussieu.fr Supplementary information: Supplementary data are available at Bioinformatics online.
Reference Key
openalex_W2152026276 Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Gabriela Bindea, Jérôme Galon, Bernhard Mlecnik
Journal BMC Bioinformatics
Year 2013
DOI
10.1093/bioinformatics/btt019
URL
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