MSstats: an R package for statistical analysis of quantitative mass spectrometry-based proteomic experiments

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ID: 298660
2014
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Abstract
MSstats is an R package for statistical relative quantification of proteins and peptides in mass spectrometry-based proteomics. Version 2.0 of MSstats supports label-free and label-based experimental workflows and data-dependent, targeted and data-independent spectral acquisition. It takes as input identified and quantified spectral peaks, and outputs a list of differentially abundant peptides or proteins, or summaries of peptide or protein relative abundance. MSstats relies on a flexible family of linear mixed models.The code, the documentation and example datasets are available open-source at www.msstats.org under the Artistic-2.0 license. The package can be downloaded from www.msstats.org or from Bioconductor www.bioconductor.org and used in an R command line workflow. The package can also be accessed as an external tool in Skyline (Broudy et al., 2014) and used via graphical user interface.
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openalex_W2114165700 Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Meena Choi, Ching-Yun Chang, Timothy Clough, Daniel Broudy, Trevor Killeen, Brendan MacLean, Olga Vitek
Journal BMC Bioinformatics
Year 2014
DOI
10.1093/bioinformatics/btu305
URL
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