BamTools: a C++ API and toolkit for analyzing and managing BAM files

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ID: 298604
2011
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Abstract
Abstract Motivation: Analysis of genomic sequencing data requires efficient, easy-to-use access to alignment results and flexible data management tools (e.g. filtering, merging, sorting, etc.). However, the enormous amount of data produced by current sequencing technologies is typically stored in compressed, binary formats that are not easily handled by the text-based parsers commonly used in bioinformatics research. Results: We introduce a software suite for programmers and end users that facilitates research analysis and data management using BAM files. BamTools provides both the first C++ API publicly available for BAM file support as well as a command-line toolkit. Availability: BamTools was written in C++, and is supported on Linux, Mac OSX and MS Windows. Source code and documentation are freely available at http://github.org/pezmaster31/bamtools. Contact: barnetde@bc.edu
Reference Key
openalex_W2147841875 Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Derek W. Barnett, Erik K. Garrison, Aaron R. Quinlan, Michael P. Strömberg, Gábor Marth
Journal BMC Bioinformatics
Year 2011
DOI
10.1093/bioinformatics/btr174
URL
https://academic.oup.com/bioinformatics/article-pdf/27/12/1691/48861708/bioinformatics_27_12_1691.pdf
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