Microsatellites: Evolution and Applications

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ID: 298228
1999
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Abstract
Abstract Microsatellites are short stretches of repeated DNA, found in most genomes, that show exceptional variability in humans and most other species. This variability has made microsatellites the genetic marker of choice for most applications, including genetic mapping and studies of the evolutionary connections between species and populations. This book brings together an international group of scientists currently working in microsatellites. Their contributions provide a detailed description of microsatellite biology, focusing on their mutation properties, generation, decay, and possible functional roles. They introduce the theoretical models that underpin the most popular methods for analysing the information that microsatellites can yield, including methods for estimating coalescent times, population divergences, and migration. Finally, the book describes the various ways in which the potential of microsatellites is being harnessed in a range of applications including medical genetics, forensics, genetic mapping, the analysis of human evolution, and conservation genetics.
Reference Key
openalex_W27851543 Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors David B. Goldstein, Christian Schlötterer
Journal Oxford University Press eBooks
Year 1999
DOI
10.1093/oso/9780198504085.001.0001
URL
https://doi.org/10.1093/oso/9780198504085.001.0001
Keywords Keywords not found

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